Attività HPV Unit

 2012-2013

Human Papillomavirus DNA and PapTests: The Need for Cotesting in Opportunistic Setting During the Transition Time (L.Mariani et al. Journal of Lower Genital Tract Disease, 2013) 

Prevalence, genotypediversity and determinants of anal HPV infection in HIV-uninfected men having sex with men. Donà MG, Palamara G, Di Carlo A, Latini A, Vocaturo A, Benevolo M, Pimpinelli F, Giglio A, Moretto D, Impara G, Giuliani M. J Clin Virol. 2012 Jun;54(2):185-9 

Rome consensus conference - statement; HPV diseases in males ( A.Lenzi et al. BMC Public Health 2013)

HPV type distribution in invasive cervical cancers in Italy: pooled analysis of three large studies (P.Giorgi Rossi et al. Infectious Agents and Cancer 2012, 7:26)

A new surveillance gynecological network to assess the incidence and prevalence of genital warts in the Italian female population: lessons learned (Suligoi B et al. Minerva Ginecol. 2013 Oct;65(5):577-85.

Worldwide human papillomavirus genotype attribution in over 2000 cases of intraepithelial and invasive lesions of the vulva (S.deSanjosè et al. Eur J Cancer. 2013 Nov)

HPV Unit: a multidisciplinary model of intervention for prevention, education and health-care delivery against the Human Papillomavirus (L.Mariani et al HPV TODAY in press)

In vivo antitumor effect of an intracellular single-chain antibody fragment against the E7 oncoprotein of Human Papillomavirus 16. (Accardi L. et al Int J Cancer. 2013 Nov 13)

Identification of episomal human papillomavirus and other DNA viruses in cytological anal samples of HIV-uninfected men who have sex with men (Donà M et al PLoS One. 2013 Aug 12)

Immunotherapy in new pre-clinical models of HPV-associated oral cancers (F.Paolini et al. Hum VaccinImmunother. 2013 Jan 7)

Both mucosal and cutaneous papillomaviruses are in the oral cavity but only alpha genus seems to be associated with cancer (F. Paolini et al, J ClinVirol. 2013 Jan;56)

Chlamydomonas-derived Human Papillomavirus 16 E7 vaccine induces specific tumor protection. (OC Demurtas et al, PLoSOne. 2013 Apr 23)

 

2014 

Immunologic treatments for precancerous lesions and uterine cervical cancer.
Vici P, Mariani L, Pizzuti L, Sergi D, Di Lauro L, Vizza E, Tomao F, Tomao S, Cavallotti C, Paolini F, Venuti
J Exp Clin Cancer Res. 2014 Mar 26;33:29

Emerging biological treatments for uterine cervical carcinoma.
Vici P, Mariani L, Pizzuti L, Sergi D, Di Lauro L, Vizza E, Tomao F, Tomao S, Mancini M, Vincenzoni C, Barba M, Maugeri-Saccà M., Giovinazzo G., Venuti A.
J Cancer. 2014 Jan 5;5(2):86-97

In vivo antitumor effect of an intracellular single-chain antibody fragment against the E7 oncoprotein of human papillomavirus 16.
Accardi L, Paolini F, Mandarino A, Percario Z, Di Bonito P, Di Carlo V, Affabris E, Giorgi C, Amici C, Venuti A.
Int J Cancer. 2014 Jun 1;134(11):2742-7

Corso di aggiornamento su HPV (Istituto Europeo di Oncologia, 23 maggio 2013)

Corso della Società Italiana di Oncologia Ginecologica (SIOG) e dell'IHSG a Bari, Catania, Milano e Roma (scarica la locandina)

Workshop: role of oncogenic viruses and environmental factors in human carcinogenesis: speakers Massimo Tommasino and Aldo Venuti (Regina Elena National Cancer Inst February 13, 2014)

Screening molecolare nella prevenzione del carcinoma della cervice uterina (Istituto Nazionale Tumori Regina Elena, 23 maggio 2014) scarica il programma (under the UICC auspices)

HPV: formare per informare (Istituto Nazionale Tumori Regina Elena, 2 luglio 2014)

La vaccinazione anti-HPV universale. Il Sole 24 Ore. Quaderni Sanità Dicembre 2014. Fondazione G.Lorenzini.

 

2015

Early Direct and Indirect Impact of Quadrivalent HPV (4HPV) Vaccine on Genital Warts: a Systematic Review.
Luciano Mariani, Patrizia Vici, Barbara Suligoi, Giovanni Checcucci-Lisi, Rosybel Drury.
Adv Ther (2015) 32:10–30

Performance of HPV DNA testing in the follow-up after treatment of high-grade cervical lesions, adenocarcinoma in situ (AIS) and microinvasive carcinoma.
Silvano Costa, Simona Venturoli, Massimo Origoni, Mario Preti, Luciano Mariani, Paolo Cristoforoni and Maria Teresa Sandri.
ecancer 2015, 9:528

Public health value of universal HPV vaccination.
Riccardo A. Audisio , Giancarlo Icardi, Andrea M. Isidori, Carlo A. Liverani, Alberto Lombardi, Luciano Mariani, Francesco Saverio Mennini, David A. Mitchell, Andrea Peracino, Sergio Pecorelli, Giovanni Rezza, Carlo Signorelli, Giovanni Vitali Rosati, Gian Vincenzo Zuccotti
Crit Rev Oncol/Hematol (2015)

VIN usual type—from the past to the future.
Mario Preti, Sarah Igidbashian, Silvano Costa, Paolo Cristoforoni, Luciano Mariani, Massimo Origoni, Maria T Sandri, Sara Boveri, Noemi Spolti, Laura Spinaci, Francesca Sanvito, Eleonora P Preti, Adriana Falasca, Gianluigi Radici and Leonardo Micheletti
ecancer 2015, 9:531

HPV-testing in follow-up of patients treated for CIN2+ lesions.
Luciano Mariani, Maria Teresa Sandri, Mario Preti, Massimo Origoni, Silvano Costa, Paolo Cristoforoni, Fabio Bottari and Mario Sideri.
Journal of Cancer, 2015 (in press)

ERK1-Based Pathway as a New Selective Mechanism To Modulate CCR5 with Natural Antibodies.
Venuti A, Pastori C, Siracusano G, Riva A, Sciortino MT, Lopalco L.
J Immunol. 2015 Oct 1;195(7):3045-57.

Mucosal Alpha-Papillomavirus (HPV89) in a rare skin lesion.
Paolini F, Cota C, Amantea A, Curzio G, Venuti A.
Virol J. 2015 Jul 7;12:105.

Immunotherapy of HPV-associated cancer: DNA/plant-derived vaccines and new orthotopic mouse models.
Venuti A, Curzio G, Mariani L, Paolini F.
Cancer Immunol Immunother. 2015 Oct;64(10):1329-38

A prime/boost strategy using DNA/fowlpox recombinants expressing the genetically attenuated E6 protein as a putative vaccine against HPV-16-associated cancers.
Bissa M, Illiano E, Pacchioni S, Paolini F, Zanotto C, De Giuli Morghen C, Massa S, Franconi R, Radaelli A, Venuti A.
J Transl Med. 2015 Mar 5;13:80

The L1 protein of human papilloma virus 16 expressed by a fowlpox virus recombinant can assemble into virus-like particles in mammalian cell lines but elicits a non-neutralising humoral response.
Bissa M, Zanotto C, Pacchioni S, Volonté L, Venuti A, Lembo D, De Giuli Morghen C, Radaelli A.
Antiviral Res. 2015 Apr;116:67-75

Anti-tumor effects of genetic vaccines against HPV major oncogenes.
Cordeiro MN, Paolini F, Massa S, Curzio G, Illiano E, Duarte Silva A, Franconi R, Bissa M, Morghen Cde G, de Freitas AC, Venuti A.
Hum Vaccin Immunother. 2015;11(1):45-52